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Gaosiga Tu'uina atu Cilengitide 98% pa'epa'e pa'epa'e CAS NO.188968-51-6 Ata Fa'aalia
  • Gaosiga Tu'uina atu Cilengitide 98% pa'epa'e pa'epa'e CAS NO.188968-51-6
  • Gaosiga Tu'uina atu Cilengitide 98% pa'epa'e pa'epa'e CAS NO.188968-51-6
  • Gaosiga Tu'uina atu Cilengitide 98% pa'epa'e pa'epa'e CAS NO.188968-51-6

Gaosiga Tu'uina atu Cilengitide 98% pa'epa'e pa'epa'e CAS NO.188968-51-6

Cilengitide CAS NO:188968-51-6
Cilengitide o se peptide cyclic pentapeptide e tauva mo le arginine-glycine-aspartate (RGD) peptide sequence.Fa'atonu le fusifusia integrin-ligand.Cilengitide filifili ma le lelei e taofiofia le alpha v beta 3 beta ma le alpha v 5 integrin faʻatasi ma matrix proteins, e pei o Vitronectin, Fibronectin, Fibrinogen, vonWillebrandFactor, Osteopontin, ma isi.O le 10μMCilengiChemicalbooktide e taofia atoa le pipii o sela BAE, BME ma HUVE i Vitronectin ma Fibronectin.Cilengitide galue in vitro i luga o sela BAE muai togafitia i le FGF-2(poʻo le VEGF-A) o le tolu-dimensional collagen ma le toto fibrin gel e taofia le angiogenesis ma IC50 o le 15 ma le 8μM, ma le 4 ma le 3μM, faasologa.O le Cilengitide e fa'alavelaveina le fa'atuputeleina o le sela, fa'aosofia ai le apoptosis o le endothelial cell, ma fa'aosoina le eseesega o le cell endothelial precursor.


Fa'amatalaga Oloa

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Igoa Oloa Cilengitide
CAS 188968-51-6
fua mole mole C27H40N8O7
mamafa mole 588.66
mafiafia 1.41±0.1 g/cm3(Va'ai)
solubility ≥29.43 mg/mL ile DMSO;≥22.56 mg/mL ile H2O
Su'ega oona (pKa) 4.01±0.10(Vavaloa)
config (1)
config (1)
config (2)

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